Thank you to our customers and partners!
This year, nanoplus celebrated the 20 years anniversary of its founding as well as the 10 year anniversay of
its subsidiary in Meiningen.
In 1998, nanoplus started with the commercial production of laterally coupled distributed feedback lasers.
Our devices feature
• all λ from 760 nm to 14 μm
• large tuning coefficient
• customized solutions which fit into your idea
We are proud that our DFB lasers paved the way for numerous
gas sensing applications in the industry which became
Neo-Lung - medical technology system for diagnosis of lungs in premature infants
Completion of a three-year European project for pulmonary diagnosis of early-born children.
Since 2015, GPX Medical has coordinated a three-year research project funded through the European Eurostars Program - Neo-Lung. Collaborative partners in the project have been Lund University in Sweden, the Norwegian company Norsk Elektro Optikk, and the German laser company nanoplus. The project is officially closed on 31 December 2018, but on 19-20 November, a final meeting of the project was held in Lund. At the same time, a clinical study is concluded as part of the project at Skåne University Hospital in Lund.
The project's goal has been to develop a medical technology system for diagnosis of lungs in premature infants. Very early born infants - born before pregnancy week 30 - often suffer from complications in the lungs because they are not fully developed. To facilitate breathing, respirators and oxygen in combination with medicines are used. One problem in today's care is to properly diagnose the condition of the lungs so that correct actions can be taken.
In the Neo-Lung project, a system has been developed which is based on the laser spectroscopic analysis technique the parent company of GPX Medical, Gasporox, develops and commercializes. The technology provides the possibility to monitor the oxygen concentration in the lungs using low intense light.
During the course of the project, considerable progress has been made to develop the performance of measurement technology and to develop a medical device suitable for clinical use. The design of the light-source and detector probes is cruicial for the acceptance of the technology and substantial effort has been put into the development of small and lightweight probes to be placed on the chest.
The resulting system is called NEOLA, NEOnatal Lung Analyser, and the system has undergone extensive pre-clinical tests. Among other things, a whole new type of 3D-printed tissue fantomas in polymeric materials has been developed to mimic live lung tissue in infants.
At the end of the project, a clinical study is currently underway at Skåne University Hospital in Lund. The study includes about 15 full-grown healthy babies, 1-2 days old. After approval of the parents, test measurements are made on the children's lungs to evaluate the possibilities of the technique. The preliminary results show that the technique works and can measure the presence of oxygen in the lungs.
Vineta Fellman, Professor of Neonatology and Clinical Project Party, comments:
"This is a big step toward a clinically useful method of monitoring the gas content in the lungs to improve detection of pulmonary complications, while avoiding ionizing radiation”
After the end of the Neo-Lung project, GPX Medical, together with the clinical researchers at Lund University, plans to proceed and carry out further studies. At Norsk Elektro-Optikk and Nanoplus, there is further improved electronics and laser technology that can be used to upgrade the NEOLA system and achieve even better performance.
"There are very promising results made in the project," says Märta Lewander Xu, CEO of GPX Medical. "Thanks to the fine work done by all partners, we have a clinically functioning system. The project has already received several scientific articles published. Now we will improve the system further with the technical components developed in the last months of the project, while planning for further clinical studies. "
The goal of GPX Medical is to launch a medical device for use in the monitoring of lungs in neonatal departments.
Published manuscripts related to the Neo-Lung project:
1. Development of a 3-dimensional tissue lung phantom of a preterm infant for optical measurements of oxygen-Laser-detector position considerations.
Larsson J, Liao P, Lundin P, Krite Svanberg E, Swartling J, Lewander Xu M, Bood J, Andersson-Engels S.
J Biophotonics. 2018 Mar; 11(3)
2. Computer simulation analysis of source-detector position for percutaneously measured O2 -gas signal in a three-dimensional preterm infant lung.
Liao P, Larsson J, Krite Svanberg E, Lundin P, Swartling J, Lewander Xu M, Bood J, Andersson-Engels S.
J Biophotonics. 2018 Nov;11(11)
Congratulations ESA on Sentinel-5P take off
Fascination space - after the launch of the Mars Rover in November 2011, nanoplus lasers are again part of a prestigious space project. This time, our lasers are on board of the TROPOMI (Tropospheric Monitoring Instrument) which is the single payload of the Copernicus Sentinel-5 Precursor satellite.
nanoplus congratulates the project team under The Netherlands and ESA aegis to the successful launch of its Copernicus satellite on October 13th, 2017, from Plesetsk, Russia.
We are excited that our lasers are part of this important mission on monitoring air quality around the globe. According to the project motto "Observing our future", we will follow Tropomi's results with great interest.
Observing our future - TROPOMI
TROPOMI will monitor air quality around the earth to cater the scientific and operational community, which is involved in climate and weather. The data it collects will help to refine e. g. air quality forecasts, environmental hazard and UV warnings as well as operational weather forecasts. A further major objective of the mission is to better evaluate the impact of trace gas emissions on climate change.
On a daily basis, Tropomi will quantify the principal tropospheric pollutants: O3, NO2, CO, HCHO and SO2. At the same time, it will measure the two main greenhouse gases, tropospheric O3 and CH4. Various parameters of aerosols will equally be examined, as they influence climate change and pollution of the troposphere.
According to ESA TROPOMI is a "space-borne, nadir-viewing, imaging spectrometer sensing ultraviolet (UV), visible (VIS), near (NIR) and short-wavelength infrared (SWIR)". With passive remote sensing techniques TROPOMI determines at the top of atmosphere the solar radiation reflected by and radiated from earth.
The Copernicus satellite pioneers a series of atmospheric composition Sentinels and has started on a mission of seven years. It is a joint project of Airbus Defence and Space, KNMI (The Royal Netherlands Meteorological Institute), SRON (Netherlands Institute for Space Research) and TNO (The Netherlands Organisation for applied scientific research). The space mission was assigned by NSO (Netherlands Space Office) and ESA (European Space Agency).
nanoplus America, Inc.
nanoplus has recently opened a subsidiary in Boulder, Colorado, which will cater the American market.
At nanoplus, we are convinced that personal contact is essential to understand and solve your laser needs. We have made the experience with many customers that laser specifications are best discussed on-site - in your laboratory or production unit. The insight into the technological particularities of your product allows us to design a tailor-made laser for you.
nanoplus, hence, decided to open a subsidiary in the United States, where the need for our lasers has been growing at accelerating speed. We will support our US customers with more comprehensive service on the spot, faster delivery time and immediate accessibility.
Face-to-face communication is the key for us to create a long lasting customer relationship with you based on mutual trust.
Visit or contact nanoplus America, Inc.:
|nanoplus America, Inc.|
777 29th Street, Suite 100
Boulder, Colorado, 80303
Collaboration with Automotive Coalition for Traffic Safety (ACTS)
GERBRUNN, GERMANY - nanoplus is proud to expand its collaboration with the Automotive Coalition for Traffic
Safety (ACTS) in the United States. In May 2016, ACTS officially authorized nanoplus to start the second phase of developing innovative lasers for a touch-based alcohol sensor in cooperation with TK Holdings Inc. and TruTouch Technologies, Inc.. This project is part of the U.S Department of Transportation’s National Highway Traffic Safety Administration’s (NHTSA) program for a Driver Alcohol Detection System for Safety (DADSS).
Photo: Agreement between ACTS and nanoplus;
from left to right:
Michael Willis (KEA Technologies for ACTS),
Lars Hildebrandt (nanoplus), Len Cech (TK Holdings),
Abdullatif Zaouk (KEA Technologies for ACTS),
Johannes Koeth (nanoplus), Michael Legge (nanoplus),
Derek Treese (TruTouch), Christian Forchel (nanoplus)
DADSS focuses on the development of technology that will prevent alcohol–impaired drivers from moving their cars. When ready, the alcohol detection system will be made available as a safety option in new vehicles – like automatic braking, lane departure warning, and other advanced driver assist vehicle technologies.
In 2014, 9,967 people were killed in the United States in car crashes involving drunk drivers. In the past 30 years, 401,404 people have died in drunk-driving crashes. With an accurate and reliable alcohol detection system, such numbers could soon belong to the past.
Two different technologies that measure the driver’s blood alcohol content are being research: a breath-based system, placed in the driver’s side door or in the steering column, which will measure the concentration of alcohol molecules in the driver’s exhaled breath; and a touch-based system that measures alcohol content by shining a beam of infrared light onto a driver’s fingertip when it is placed on the car’s ignition button or on the gear shift.
A video published by the DADSS research program illustrates these technologies. More information may be found at www.dadss.org.
nanoplus is excited to contribute to this life saving project with our know-how as a specialist for semiconductor lasers.